having graduated with a degree in graphic design in 2002, i wondered the same question. it didn’t stop me though as i just got back from my first summer season at the south pole.
mostly i would suggest being willing to accept the fact that there are not any design-related jobs and start digging through your previous work experience for other possible positions.
if you’ve experience (and can prove it) with physical labor and/or trade skills try for the GA (general assistant) positions or for any trade jobs you might qualify for. If you’ve previous experience in food service, consider those positions. Go for anything other than a DA (dining attendent) first though, lest you want to spend 60 hours a week washing dishes. granted, that’s what i did – antarctica exists as one of the few places where you’ll find dishwashers with bachelors and masters degrees. i would also second the recommendation to look into IT work if you have enough history with computers to qualify for a position there.
it took me two years of applying and “harassing” people at the job fair, but it worked. once you’ve made it, you end up with plenty of new opportunities as well.
again, if you can make it to any job fair offered, but particularly the denver one, you have a hand up on most folk.
best of luck,